منابع مشابه
Gut Bacteria and Melamine Toxicity
Melamine and its potential toxicity have drawn increased attention since a 2008 crisis in China in which milk, infant formula, and other foods were illegally laced with the chemical in order to increase their apparent protein content. That contamination affected an estimated 294,000 infants and children, with more than 50,000 hospitalizations and at least 6 deaths. In a new analysis of specific...
متن کاملOvarian Toxicity in Female Rats after Oral Administration of Melamine or Melamine and Cyanuric Acid
Although the toxicity of melamine to the kidneys and testes is well known, few studies have investigated the effects of melamine on female reproductive organs. Therefore, this study explores the effects of oral administration melamine or melamine and cyanuric acid for 28 days on the ovaries of female rats. Rats that were exposed to the mixture exhibited reduced ovarian and uterine weights, a sh...
متن کاملIn vitro toxicity of melamine against Tetrahymena pyriformis cells
This study assessed the toxicity of melamine against the unicellular eukaryotic system of Tetrahymena (T.) pyriformis exposed to 0, 0.05, 0.25, 0.5, 2.5, and 5 mg/mL of melamine. Cell growth curves of different cultures, the half maximum inhibition concentration (IC(50)) value of melamine, and morphological changes in cells were obtained via optical and transmission electron microscopic observa...
متن کاملMelamine-induced renal toxicity is mediated by the gut microbiota.
Melamine poisoning has become widely publicized after a recent occurrence of renal injury in infants and children exposed to melamine-tainted milk in China. This renal damage is believed to result from kidney stones formed from melamine and uric acid or from melamine and its cocrystallizing chemical derivative, cyanuric acid. However, the composition of the stones and the mechanism by which the...
متن کاملBees' Honey Protects the Liver of Male Rats against Melamine Toxicity
The protective effect of natural bees' honey to the liver of male albino rats against melamine toxicity was studied. Melamine supplementation at a dose of 20000 ppm in the diet for 28 days induced adverse effects on the liver, decreased serum total protein and increased liver enzyme: alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase. Histological changes of the mela...
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ژورنال
عنوان ژورنال: Journal of Medical Toxicology
سال: 2010
ISSN: 1556-9039,1937-6995
DOI: 10.1007/s13181-010-0038-1